PEPTIDES

Peptide Therapy

In recent years, the use of peptides in health care has gained much popularity. Peptide therapy is generally considered safe and can be used to produce very specific effects. Many peptides have been approved by the FDA allowing them to be utilized for medical trials and use.

What are Peptides?

Peptides are chains of amino acids. These are linked together in a specific process to produce a protein. Some peptides are naturally occurring and others can be artificially synthesized in the laboratory.

The body uses these proteins or peptides as signaling molecules facilitating the cell-to-cell communication and allowing the body to switch certain cell functions on or off. This property can be harnessed and used to trigger specific therapeutic effects.

What is Peptide Therapy?

Peptide therapy is the targeted use of peptides to produce a specific reaction in the body. Some peptides have been shown to assist with weight loss by stimulating the breakdown of visceral fat. They may also be utilized to reduce inflammation. Some peptides stimulate the production of human growth hormone and are utilized in anti-aging therapies or to increase muscle mass. Peptides are typically administered through the skin as a subcutaneous injection. They can also be applied in a cream, a nasal spray or in oral form.

Who May Benefit From Peptide Therapy?

Peptides may help regulate processes within the body. Patients with Lyme disease, chronic inflammation, autoimmune disease and other chronic degenerative diseases may benefit from including peptides in their treatment regimen.

Peptides we offer:

AOD-9604: Subq, topical

  • Enhanced Cartilage Regeneration
  • Increases bone formation and mineralization
  • Reduces Collagenase
  • Promotes myoblast differentiation (muscles)
  • Stimulates adipose derived mesenchymal stem cells
  • Promotes Chondrocyte Production (found in cartilage)
  • Anti Osteoporosis
  • Anti Sarcopenia Can combine with Hyaluronic Acid
  • Research -Weight loss; Phase 2 trial failed

DESCRIPTION

AOD 9604 is a modified form of amino acids 176-191 of the GH polypeptide. Investigators at Monash University discovered that the fat-reducing effects of GH appear to be controlled by a small region near one end of the GH molecule. This region, which consists of amino acids 176-191, is less than 10% of the total size of the GH Molecule and appears to have no effects on growth or insulin resistance. This hypothesis was proven in animals to a tremendous degree with specimen losing a significant amount of fat mass. However, in phase three clinical trials the peptide didn’t mean its confidence interval. Instead, it is now being studied for its effect on bone and cartilage. AOD 9604 possesses many other regenerative properties associated with growth hormone. Currently trials are underway to show the application of AOD 9604 in osteoarthritis, Hypercholesterolemia, bone and cartilage repair. AOD 9604 has an excellent safety profile, recently obtaining Human GRAS status in the USA.

“This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.”

Oral and Sub-q -repair activity shown in:

  • Gastrointestinal tract
  • Ligaments
  • Skin
  • Tendons
  • Muscles
  • Bones
  • Nerves
  • Cornea
  • Brain
  • Blood Vessels

Oral, topical

  • Improves Cognitive Function in Animal Models of Alzheimer’s disease
  • 7X more potent than Brain Derived Neurotrophic Factor (BDNF)
  • Modulates Hepatocyte Growth Factor (HGF) -HGF found during brain recovery
  • Reversal in animal models of damage to 60% of cerebral neurons
  • Induces Dendritic Arborization (Branching)
  • Induces Dendritic Synaptogenesis
  • > 5 hr ½ life
  • Crosses Blood Brain Barrier (BBB)
  • Anti Dementia Activity
  • Parkinson’s Disease Applications

Sub-q, topical; Foam & Cream

  • Stimulates collagen and glycosaminoglycan in skin fibroblasts
  • Attracts immune cells and endothelial cells – accelerates wound healing
  • Anti Anxiety
  • Hair Growth & Increase in Follicle Size
  • Improves Skin Elasticity
  • Promotes Blood Vessel Growth
  • Reduces Skin Wrinkles & Lines
  • Potent Anti Inflammatory
  • Stimulates Nerve Outgrowth
  • Improves wound healing

PT-141: Sub-q

  • Central Melanocortin Receptor Agonist
  • CNS Activity
  • Effective on Male and Female Patients
  • Increases Desire
  • Minutes to Hours Onset
  • Erectile Dysfunction Benefits
  • No Contraindications
  • Improved Delivery in R&D @ WPN
  • FDA Approved as Vyleesi for Hypoactive Sexual Desire Disorder (HSDD)
  • Statistical Improvement in Sexual Experience
  • Selank was traditionally prescribed for its anti-anxiety and antidepressant effects, however, more research has shown that Selank has more benefits including:
    • Immune modulation
    • Anticoagulation
    • PTSD, ADHD treatment
    • Metabolic syndrome treatment
    • Nootropic action- positively influences formation of memory and learning processes
  • Selank has pronounced anxiolytic activity as well as neuropsychotropic, antidepressant and anti-stress effects.
  • The anxiolytic effects are similar to benzodiazepines without the unwanted side effects of BZDs including: amnesia, withdrawal and dependence.

“This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.”

SEMAX (MEHFPGP) is the analogue of ACTH (4-10) that has a demonstrated prolonged neurotropic activity. This has historically been used in patients with pathologies related to brain circulation dysfunction. It has also been suggested in literature that due to its effect on carboxypeptidase it may also increase physical performance and adaptation capacities in exposure to high intensity exercise and at higher doses, >0.5 mg/kg, may exhibit analgesic like effects.

“This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.”

Sub-q

  • Restores Immune Function
  • Cancer Clinical Data; Lung, Colon, Breast
  • Stimulates Cytokine Secretion
  • Tumor Penetrating
  • Treating Sepsis
  • Enhances vaccination
  • Cystic Fibrosis
  • Chronic Fatigue Disease
  • Lyme Disease
  • FDA Approved as Zadaxin -hepatitis

DESCRIPTION

Thymosin Alpha 1 (TA1) is a peptide originally isolated from thymic tissue and is a compound believed to be responsible for restoring immune function in thymectomized mice. Thymosin Alpha 1 has been shown to have a pleiotropic mechanism of action and affects multiple immune cell subsets that are involved in immune suppression. Studies have demonstrated improvements in immune system cell subsets and the potential of TA1 for the treatment of a range of diseases. Thus, Thymosin Alpha 1, due to the immune stimulating effects exhibited by TA1, may have utility for the treatment of age or disease related immune suppression.

“This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.”

Sub-q

  • Regulates Actin – cell building protein
  • Wound Healing
  • Increase in stem cells
  • Improves Collagen Structure
  • Enhanced Cell Migration
  • Promotes Angiogenesis
  • Hair Growth
  • Potent Anti Inflammatory
  • Restores Neurons post-TBI
  • Prevents Adhesions of Injured Tissues
  • Zinc and thymulin are two natural compounds involved in hair follicle growth and have been studied and found to promote hair growth.
  • Combined into a spray solution, Zinc/Thymulin can be applied to the scalp and treat hair loss, bald patches and initiate the angen hair growth phase (the active growth phase of hair follicles during which the root of the hair is dividing rapidly).

“This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.”